Sickboy follows 29-year-old Jeremie Saunders as he lives openly with Cystic Fibrosis and devotes his life to removing the stigma attached to chronic illness and disease. Jeremie’s life expectancy is shortened. The film traces the efforts by Jeremie and his best friends, Brian and Taylor, to create a podcast that seeks to change the way people view serious illness, like brain cancer, depression, and epilepsy. Jeremie has shown his friends that laughing about the absurdity of his illness can take away its power. Their podcast starts to have a transformative effect on its thousands of listeners.